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39 , 40 Moreover, vitamin deficiency is a common condition in patients with cancer, and anti‐neoplastic syndrome medications can also improve vitamin C deficiency and well‐being
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Metabolic Pathway of Succinic Acid Production by Citrate Synthase (gltA) (Mutyala S et al., 2023) Regulatory Mechanisms Citrate synthase activity is modulated by several interconnected factors: Allosteric Suppression : Elevated intracellular ATP, NADH, or succinyl-CoA levels—indicators of energy surplus—bind to citrate synthase, inducing conformational changes that reduce substrate affinity
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