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In fact, in mice, depletion of the mitochondrial transcription factor A (TFAM), which controls transcription, replication and 3D structure of the mitochondrial genome, caused the activation of the cGAS-STING inflammatory pathway
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[DOI] [PubMed] [Google Scholar] 36.Zhu S, Stroebel D, Yao CA, Taly A, Paoletti P
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