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The PPP pathway in the cytoplasm is one of the main ways to produce NADPH, with the main rate-limiting enzymes being glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH)
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High-throughput screen for STX7–Munc13-4 inhibitors Late endosome-initiated proinflammatory signaling is a central mechanism in systemic inflammation and autoimmunity
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