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These results demonstrate that the “on-off” PNT PSs in wearable microneedle patches stay active (ROS “on” state) in diseased tissue during treatment but quickly deactivate (ROS “off” state) through biodegradation after fulfilling their therapeutic role without obvious biodistribution in normal tissue, ensuring bio-safe PDT
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2019;4(19) doi: 10.1172/jci.insight.127647
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