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Typical work includes glycerol-release lipolysis assays in adipocytes, adipocyte-differentiation and lipogenesis models, side-by-side comparisons of the fragment against intact growth hormone, and structure-activity studies of the hGH lipolytic domain

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628 Interestingly, low concentrations of TNF-α can induce hepatocyte proliferation by activating YAP, whereas high concentrations trigger cell death by inducing phosphorylation and inactivation of YAP following APAP treatment