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In addition, it has been previously shown that lysosomal proteins, including the heteromeric isoform of the β-hexosaminidase enzyme (HexA) can be taken up into cells via the cation-independent mannose-6-phosphate receptor (CI-MPR) expressed on the cell surface, which may be mediated by CME 146,147

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Potential side effects include gastrointestinal issues, allergic reactions, and skin rashes