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this response is a measure of the capacity of the anterior pituitary to produce ACTH and this has been adopted for clinical use as a diagnostic test Indications: Diagnostic test of pituitary function May be useful for reducing cortisol production to normal levels in Cushing's syndrome A normal response (reduction in cortisol or its metabolites in urine) indicates that the elevated cortisol levels are not due to a cortisol-secreting adrenal carcinoma or adenomal, since secretion by such tumors produces suppression of ACTH & atrophy of normal adrenal cortex Side Effects: transient dizziness & GI disturbances Pronunciation : me TEER a pone OR me TIE ra pone Reference: