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Identification of defect in the genes for bilirubin UDP-glucuronosyl-transferase in a patient with Crigler–Najjar syndrome type II
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Specifically, only one perioperative high-dose NAC study (150 mg/kg preoperative followed by 50 mg/kg for 6 h) [52] found a significant reduction in perioperative AKI, and all other high-dose papers with a later dosing period trended toward AKI reduction, even though not all reached statistical significance
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