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Pharmakologie der Nichtopioidanalgetika | Der Schmerz | Springer Nature Link

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Researchers have seen that opioids can lead to a dehydration status (Mallappallil et al., 2017), but it should not be overlooked the fact that also ethanol ingestion affects the hypothalamo-neurohypophysial system resulting in increased diuresis, dehydration, and hyperosmolality, thus summing up the effects of dehydration to altered microbiome (Madeira et al., 1993)