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( b ) Measurement of AcH levels in serum from Aldh2 f/f mice (n = 6), Aldh2 E2a − / − mice (n = 5), and global Aldh2 KO mice (n = 4) 3 h post ethanol oral gavage (5 g/Kg)
Est_7
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Factors influencing NASH progression include lipotoxicity, endoplasmic reticulum (ER) stress, mitochondrial dysfunction, oxidative stress, gut endotoxins, and microbiota [19,25,26,27,28]
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