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Shingles - When to See a Dermatologist - Trillium Creek Dermatology

When to Contact Your Dermatologist Between scheduled appointments, it is worth contacting your dermatologist if you notice: A sudden increase in new patches or rapid spread of existing ones Redness, irritation, blistering, or pain in treated areas beyond what was expected Side effects from oral or topical treatments New symptoms that might suggest thyroid or other autoimmune disease (such as unexplained weight change, fatigue, palpitations, or feeling cold) A significant drop in mood or feelings of hopelessness related to your appearance Catching changes early often makes them easier to manage

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While this highlights the value of the murine model for pre-clinical discovery and development of a subunit vaccine for human whipworm infection, it should be noted that susceptibility and immunologic resistance/clearance of the infection is mouse strain- (median histocompatibility complex) and sex-dependent, and is influenced by the nature of exposure, notably trickle versus bolus infection (Yousefi et al., 2021)