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When the blood cannot be seen with the naked eye, it’s called microhematuria.) Possible causes of blood in the urine include: Urinary tract infection (UTI) Kidney infection Infections in the bladder, urethra, or prostate Trauma to the urinary tract Kidney stones Kidney cysts Bladder cancer Kidney cancer Prostate cancer Vaginal bleeding Endometriosis Enlarged prostate (benign prostatic hyperplasia) Benign (not cancerous) tumors Hemophilia Sickle cell disease Hard exercise, such as distance running Sexual activity If you suspect there is blood in your urine, see your doctor as soon as possible