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Most existing research has primarily focused on the electrophile and redox sensor in Kelch-like ECH-associated protein 1 (KEAP1) and its role in modulating the NRF2 protein levels in response to metabolic changes [106].The interaction between KEAP1 and NRF2 is disrupted by electrophilic alteration or oxidation of cysteine thiols in KEAP1, allowing cells to respond to environmental stress
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Quantitative determination of water- and lipid-soluble antioxidants in neoplastic and non-neoplastic human breast tissue
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