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Copper is a trace element and a critical component of many mitochondrial metalloenzymes in which it acts as an electron donor or acceptor (Stern et al., 2007), and these enzymes, such as monoamine oxidase (Kesterson and Carlton, 1971) and cytochrome c (Cyt c) oxidase (Acs et al., 2013
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2021;296 doi: 10.1074/jbc.RA120.016551
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