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The LTE randomized dose-adjusted populations included 56 participants randomized to placebo at week M-0 who had their dose adjusted to guselkumab 200 mg SC q4w, 10 randomized to guselkumab 100 mg SC q8w who had their dose adjusted to guselkumab 200 mg SC q4w, and 16 randomized to guselkumab 200 mg SC q4w who had a sham dose adjustment (Figure S1B, The LTE nonrandomized guselkumab population included 102 LTE participants assigned to receive guselkumab 200 mg SC q4w at week M-0 (Figure S1C, The LTE all treated population included 511 participants who received guselkumab (guselkumab 100 mg q8w, n = 162

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