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Current understanding of eryptosis: mechanisms, physiological functions, role in disease, pharmacological applications, and nomenclature recommendations | Cell Death & Disease

TB-500, a synthetic version of the naturally occurring Thymosin Beta-4 peptide fragment, appears to promote cell migration, differentiation, and wound healing by regulating actin polymerization and increasing vascular endothelial growth factor (VEGF) activity

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This causes SLC7A11-high cancer cells to be more dependent on the glucose pentose phosphate pathway (a major provider of NADPH in cells), which in turn is metabolically dependent on glucose ( Figure 2 )