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RCSB PDB - 2R37: Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant)
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In in vitro studies, cereblon-based PROTAC 92 (L055) was shown to induce potent antiproliferative activity (IC 50 = 29 nM in MCF-7 cells), G2/M cell cycle arrest, and decreased survival of ERα-positive breast cancer cells
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