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doi: 10.1016/j.ccell.2022.01.001 Summary Keywords metabolism, cancer, T cells, macrophages, immunotherapy, tumor microenvironment, angiogenesis Citation Wik JA, Berge ER, Stromsnes K and Skålhegg BS (2025) Metabolism in the tumor microenvironment: implications for pathogenesis and therapeutics
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Upon entering liver hepatocytes, much of the acetaminophen is conjugated to sulfate by SULTs or to glycogen-derived sugars by UDP-glucuronyltransferase and exported by multidrug resistance (MDR) or ATP-binding cassette (ABC) organic ion transporters, thereby removing oxidized sulfur and depleting energetic resources (glycogen) (56)
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