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Isocitrate dehydrogenases (IDH) IDH also facilitates the generation of NADPH from NADP + by catalyzing the oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG) for TCA cycle
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With the advent of single-cell technologies for transcriptomic and epigenetics, science has moved from bulk cellular analysis to understanding cellular heterogeneity within the same population, which needs to be adapted even in metabolism
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