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There have been identified at least four BDNF promoters in the rat (Timmusk et al., 1993), each one driving the transcription of mRNAs that contain one of the 8 non-coding exons spliced to the common 30 coding exons, which produce an heterogeneous population of BDNF transcripts

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PEDF protects retinal pigment epithelium from ferroptosis and ameliorates dry AMD-like pathology in a murine model