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Intriguingly, γ-irradiated resveratrol has a lower toxicity compared to its intact form, and has strong immunosuppressive properties as it can significantly inhibit inflammatory cytokine production, costimulatory molecule expression, and antigen-presentation by LPS-activated mouse BM-DCs ( Oral administration of γ-irradiated resveratrol attenuated the clinical signs of colitis in DSS-treated mice, suggesting the therapeutic potential of γ-irradiated resveratrol in IBD ( In silico studies have revealed that TLR4, IRAK1, and caspase-3 are molecular targets of resveratrol ( 3.4 Epigallocatechin-3-gallate Green tea ( Camellia sinensis ) is a popular beverage that is consumed worldwide for its health benefits
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The current study addressed these limitations by testing a noninvasive nasal GSH repletion strategy, and measuring CNS uptake via proton magnetic resonance spectroscopy ( 1 H-MRS)
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