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There were seven metabolic pathways screened including Phenylalanine, tyrosine and tryptophan biosynthesis, Glutathione metabolism, Phenylalanine metabolism, Lysine degradation, Cysteine and methionine metabolism, Tyrosine metabolism, and Tryptophan metabolism (Tables 3, 4)

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In particular, ischemic heart disease and/or reperfusion injury have been shown to display a hyper-oxidative state wherein increased reactive oxygen and nitrogen species (ROS/RNS) generation correlates with a worsening of myocardial injury [9-11]