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The observation lends credence to the notion that Compound I may act indiscriminately as cellular oxidant—which might justify the fact that it is maintained at a relatively low titer, ceding the responsibility for H 2 O 2 clearance to peroxidases, until H 2 O 2 levels rise to the point at which peroxidases might be overwhelmed

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Equal amounts of protein lysates were separated by 10% or 12% sodium dodecyl sulfate-polyacrylamide gel electrophoresis gel electrophoresis