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In this algorithm, the membrane (ligand) proteins were set as input whereas the transcription factors were set as output components (Table 6) of Wntsignaling network in Homo Sapiens
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In SK-N-BE cells, etorphine-induced hDOR desensitization is totally inhibited by using the dominant negative GRK2 mutant K220R but is only reduced when using PKC and tyrosine kinase inhibitors (Marie et al., 2008)
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