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The results have shown that perioperative administration of N-acetylcysteine, selenium, and vitamin C is not effective in preventing acute kidney injury following bypass surgery

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PYY probably counterregulates ghrelin release, a potent orexigenic peptide present in oxyntic mucosa and in hypothalamus (36) acting via with specific receptors (growth hormone secretagogue receptor - GHS-R) expressed in vagus nerves (37) as well as in hypothalamus (ARC), this could be due to the fact that PYY-ghrelin negative interaction occurs both at the level of vagal afferents, nodose ganglion and hypothalamus, particularly at its ARC